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Article

Estrogen receptor-beta gene disruption potentiates estrogen-inducible aggression but not sexual behaviour in male mice.

The European journal of neuroscience - 1 Apr 2006

Nomura Masayoshi, Andersson Sandra, Korach Kenneth S, Gustafsson Jan-Ake, Pfaff Donald W, Ogawa Sonoko

Abstract excerpt

Aggressive behaviour of gonadally intact male mice is increased by estrogen receptor (ER)-beta gene disruption, whereas sexual behaviour remains unchanged. The elevated aggression levels following ER-beta gene disruption is pronounced during repeated aggression tests in young animals and the first aggression test in adults. In the present study, the roles of ER-beta activation in the regulation of aggressive and...

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PMID: 16623843
DOI: 10.1111/j.1460-9568.2006.04703.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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