Article
Masculine sexual behavior is disrupted in male and female mice lacking a functional estrogen receptor alpha gene.
Hormones and behavior - 1 Dec 1997
Wersinger S R, Sannen K, Villalba C, Lubahn D B, Rissman E F, De Vries G J
Abstract excerpt
Masculine sexual behavior is regulated by testosterone (T). However, T can be metabolized to form estrogens or other androgens, which then activate their own receptors. We used knockout mice lacking a functional estrogen receptor alpha (ER alpha) gene to test the hypothesis that, following aromat...
Topics
- Animals
- Brain Chemistry
- Female
- Genotype
- Image Processing, Computer-Assisted
- Immunohistochemistry
- Male
- Mice
- Orchiectomy
- Ovariectomy
- Polymerase Chain Reaction
- Receptors, Androgen