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Article

Lack of functional estrogen receptor beta influences anxiety behavior and serotonin content in female mice.

Physiology & behavior - 31 Jan 2005

Imwalle D Bradley, Gustafsson Jan-Ake, Rissman Emilie F

Abstract excerpt

Estrogen has been linked to the modulation of anxiety in females. Here we report results of anxiety tests conducted in female estrogen receptor beta (ERbeta) knockout (ERbetaKO) and wild-type (WT) mice. Ovariectomized (OVX) mice treated with chronic estradiol (E2) replacement did not behave differently on the elevated plus-maze when compared with OVX mice that did not experience hormone replacement. However, a...

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Source

Identifiers

PMID: 15642619
DOI: 10.1016/j.physbeh.2004.11.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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