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Article

Structure of the RNA-dependent RNA polymerase from COVID-19 virus

10 Apr 2020

Abstract excerpt

A novel coronavirus [severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2)] outbreak has caused a global coronavirus disease 2019 (COVID-19) pandemic, resulting in tens of thousands of infections and thousands of deaths worldwide. The RNA-dependent RNA polymerase [(RdRp), also named nsp12] is the central component of coronaviral replication and transcription machinery, and it appears to be a primary target...

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PMID: 32277040
DOI: 10.1126/science.abb7498

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