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Article

Detailed Phenotypic and Functional Characterization of a Rare, Antibody-Dependent SLAM-Associated Protein Expression Pattern.

ImmunoHorizons - 10 Apr 2020

Khanolkar Aaruni, Wilks Jeffrey D, Liu Guorong, Caparelli Edward A, De Moura Michelle, Yap Kai Lee, Mustafa Asma, Kadri Sabah, Huang Wei, Zheng Xiaotian T

Abstract excerpt

SLAM-associated protein (SAP) is an adaptor molecule that facilitates critical effector functions in immune cells, and its deficiency causes X-linked lymphoproliferative disease type 1 in which effector responses directed against EBV are severely compromised. The primary objective of this study was to phenotypically and functionally characterize a rare, CD8 T cell-restricted bimodal SAP expression pattern...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32276922
DOI: 10.4049/immunohorizons.1900060

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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