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Article

Toxo: a library for calculating penetrance tables of high-order epistasis models.

BMC bioinformatics - 9 Apr 2020

Ponte-Fernández Christian, González-Domínguez Jorge, Carvajal-Rodríguez Antonio, Martín María J

Abstract excerpt

BACKGROUND: Epistasis is defined as the interaction between different genes when expressing a specific phenotype. The most common way to characterize an epistatic relationship is using a penetrance table, which contains the probability of expressing the phenotype under study given a particular allele combination. Available simulators can only create penetrance tables for well-known epistasis models involving a...

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Identifiers

PMID: 32272874
DOI: 10.1186/s12859-020-3456-3
PMCID: PMC7147067

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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