Article
Abo1 is required for the H3K9me2 to H3K9me3 transition in heterochromatin.
Scientific reports - 8 Apr 2020
Dong Wenbo, Oya Eriko, Zahedi Yasaman, Prasad Punit, Svensson J Peter, Lennartsson Andreas, Ekwall Karl, Durand-Dubief Mickaël
Abstract excerpt
Heterochromatin regulation is critical for genomic stability. Different H3K9 methylation states have been discovered, with distinct roles in heterochromatin formation and silencing. However, how the transition from H3K9me2 to H3K9me3 is controlled is still unclear. Here, we investigate the role of the conserved bromodomain AAA-ATPase, Abo1, involved in maintaining global nucleosome organisation in fission yeast....
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