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Article

Maintenance of meiotic crossover against reduced double-strand break formation in fission yeast lacking histone H2A.Z.

Gene - 15 Jun 2020

Yamada Takatomi, Yamada Shintaro, Ding Da-Qiao, Fujita Yurika, Takaya Emi, Hiraoka Yasushi, Murakami Hiroshi, Ohta Kunihiro

Abstract excerpt

Meiotic crossover (CO) recombination initiates from programmed DNA double-strand breaks (DSBs) around hotspots, and results in reciprocal exchange of chromosome segments between homologous chromosomes (homologs). COs are crucial for most sexually-reproducing organisms because they promote accurate chromosome segregation and create genetic diversity. Therefore, faithful accomplishment of CO formation is ensured in...

Topics

Crossing Over, Genetic
DNA Breaks, Double-Stranded
Histones
Meiosis
Mutation
Recombinational DNA Repair
Schizosaccharomyces
Schizosaccharomyces pombe Proteins

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 32222534
DOI: 10.1016/j.gene.2020.144615

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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