Vertebrate maternal‐effect genes: Insights into fertilization, early cleavage divisions, and germ cell determinant localization from studies in the zebrafish

Abstract excerpt

In the earliest stages of animal development prior to the commencement of zygotic transcription, all critical cellular processes are carried out by maternally-provided molecular products accumulated in the egg during oogenesis. Disruption of these maternal products can lead to defective embryogenesis. In this review, we focus on maternal genes with roles in the fundamental processes of fertilization, cell...

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