Kinase activity-dependent nuclear export opposes stress-induced nuclear accumulation and retention of Hog1 mitogen-activated protein kinase in the budding yeast Saccharomyces cerevisiae.

doi:10.1091/mbc.10.4.1147

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Article

Kinase activity-dependent nuclear export opposes stress-induced nuclear accumulation and retention of Hog1 mitogen-activated protein kinase in the budding yeast Saccharomyces cerevisiae.

Molecular biology of the cell - 1 Apr 1999

Reiser V, Ruis H, Ammerer G

Abstract excerpt

Budding yeast adjusts to increases in external osmolarity via a specific mitogen-activated protein kinase signal pathway, the high-osmolarity glycerol response (HOG) pathway. Studies with a functional Hog1-green fluorescent protein (GFP) fusion reveal that even under nonstress conditions the mitogen-activated protein kinase Hog1 cycles between cytoplasmic and nuclear compartments. The basal distribution of the...

Topics

Base Sequence
Calcium-Calmodulin-Dependent Protein Kinases
Cell Nucleus
DNA Primers
Genotype
Glycerol
Green Fluorescent Proteins
Hypertonic Solutions
Kinetics
Luminescent Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mitogen-Activated Protein Kinases

Models, Biological

Molecular Sequence Data

Osmolar Concentration

Phosphorylation

Polymerase Chain Reaction

Promoter Regions, Genetic

Recombinant Fusion Proteins

Source

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Identifiers

PMID: 10198063
DOI: 10.1091/mbc.10.4.1147
PMCID: PMC25242

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-10198063-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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