Article
An update on the monogenic causes of Parkinson's disease: Impact on patient stratification and personalised medicine.
Ageing research reviews - 1 Jun 2026
Asmi Sakeena, Krishnan Anand, Alexander Sneha Mary, Mohamed Ameer Jimna, Nidhish T, Sreetama Sen Chandra, Keerthi T R, Shenoi Rajesh A, Chakravarthy Sg S, Chandra Goutam
Abstract excerpt
Parkinson's disease (PD) is a complex neurodegenerative disorder with both genetic and environmental contributions. Over the past two and a half decades, advances in genetics, genomics and molecular biology have uncovered several monogenic forms of PD, linked to mutations in a number PD genes (collectively called PARK genes) such as SNCA, LRRK2, PRKN, PINK1, and DJ-1. To date there are 26 PARK genes reported with...
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