Molecular pathogenesis of Parkinson's disease: update.

doi:10.1136/jnnp-2011-301205

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Article

Molecular pathogenesis of Parkinson's disease: update.

Journal of neurology, neurosurgery, and psychiatry - 1 Apr 2012

Saiki Shinji, Sato Shigeto, Hattori Nobutaka

Abstract excerpt

Parkinson disease (PD) is a neurodegenerative disease characterised by progressive disturbances in motor, autonomic and psychiatric functions. Much has been learnt since the disease entity was established in 1817. Although there are well established treatments that can alleviate the symptoms of PD, a pressing need exists to improve our understanding of the pathogenesis to enable development of disease modifying...

Topics

Endoplasmic Reticulum-Associated Degradation
F-Box Proteins
Genetic Predisposition to Disease
Genome-Wide Association Study
Group VI Phospholipases A2
Humans
Intracellular Signaling Peptides and Proteins
Leucine-Rich Repeat Serine-Threonine Protein Kinase-2
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Oncogene Proteins

Parkinson Disease

Protein Deglycase DJ-1

Protein Kinases

Protein Serine-Threonine Kinases

Proton-Translocating ATPases

Ubiquitin

Ubiquitin-Protein Ligases

alpha-Synuclein

Source

Open in PubMed

Identifiers

PMID: 22138181
DOI: 10.1136/jnnp-2011-301205

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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