Article
Genetic Risk Profiling in Parkinson's Disease and Utilizing Genetics to Gain Insight into Disease-Related Biological Pathways.
International journal of molecular sciences - 4 Oct 2020
Hall Ashley, Bandres-Ciga Sara, Diez-Fairen Monica, Quinn John P, Billingsley Kimberley J
Abstract excerpt
Parkinson's disease (PD) is a complex disorder underpinned by both environmental and genetic factors. The latter only began to be understood around two decades ago, but since then great inroads have rapidly been made into deconvoluting the genetic component of PD. In particular, recent large-scale projects such as genome-wide association (GWA) studies have provided insight into the genetic risk factors associated...
Topics
- Genetic Predisposition to Disease
- Genome-Wide Association Study
- Humans
- Parkinson Disease
- Polymorphism, Single Nucleotide
- Risk Factors
- Signal Transduction