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Article

TAS2R38 is a novel modifier gene in patients with cystic fibrosis

2 Apr 2020

Abstract excerpt

The clinical manifestation of cystic fibrosis (CF) is heterogeneous also in patients with the same cystic fibrosis transmembrane regulator (CFTR) genotype and in affected sibling pairs. Other genes, inherited independently of CFTR, may modulate the clinical manifestation and complications of patients with CF, including the severity of chronic sinonasal disease and the occurrence of chronic Pseudomonas aeruginosa...

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PMID: 32242045
DOI: 10.1038/s41598-020-62747-9

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