Article
An open-access dashboard to interrogate the genetic diversity of Mycobacterium tuberculosis clinical isolates.
Scientific reports - 21 Oct 2024
Phelan Jody, Van den Heede Klaas, Masyn Serge, Verbeeck Rudi, Lamprecht Dirk A, Koul Anil, Wall Richard J
Abstract excerpt
Tuberculosis (TB) remains one of the leading infectious disease killers in the world. The ongoing development of novel anti-TB medications has yielded potent compounds that often target single sites with well-defined mechanisms of action. However, despite the identification of resistance-associated mutations through target deconvolution studies, comparing these findings with the diverse Mycobacterium tuberculosis...
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