Article
Molecular analysis of polymyxin B resistance in clinical carbapenem-resistant Klebsiella pneumoniae isolates from a large tertiary care teaching hospital in Southwest China.
BMC microbiology - 20 May 2026
Wu Siying, Liao Quanfeng, Liu Ya, Deng Jin, Zhang Weili, Kang Mei
Abstract excerpt
BACKGROUND: This study aimed to investigate the molecular basis of polymyxin B resistance in clinical carbapenem-resistant Klebsiella pneumoniae (CRKP) isolates. METHODS: A total of 52 polymyxin B-resistant CRKP clinical isolates were collected at West China Hospital between 2018 and 2021. Polymy...
Topics
- Polymyxin B
- China
- Klebsiella pneumoniae
- Microbial Sensitivity Tests
- Anti-Bacterial Agents
- Humans
- Klebsiella Infections
- Bacterial Proteins
- Hospitals, Teaching
- Tertiary Care Centers
- beta-Lactamases
- Whole Genome Sequencing
- Carbapenems
- Drug Resistance, Bacterial