Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tumor-Infiltrating T Cells From Clear Cell Renal Cell Carcinoma Patients Recognize Neoepitopes Derived From Point and Frameshift Mutations

12 Mar 2020

Abstract excerpt

Mutation-derived neoantigens are important targets for T-cell mediated reactivity towards tumors and, due to their unique tumor expression, an attractive target for immunotherapy. Neoepitope-specific T cells have been detected across a number of solid cancers with high mutational burden tumors, but neoepitopes have been mostly selected from single nucleotide variations (SNVs), and little focus has been given to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Cancer Immunotherapy and Biomarkers
Share to CAR-T cell therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32226429
DOI: 10.3389/fimmu.2020.00373

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tumor-Infiltrating T Cells From Clear Cell Renal Cell Carcinoma Patients Recognize Neoepitopes Derived From Point and Frameshift MutationsPMID 32226429Read ↗

Insertion-and-deletion-derived tumour-specific neoantigens and the immunogenic phenotype: a pan-cancer analysis.Semantic proximity Read ↗

INAEME: Integral Neoantigen Analysis with Entirety of Mutational EventsSemantic proximity Read ↗

Sources of Cancer Neoantigens beyond Single-Nucleotide Variants.Semantic proximity Read ↗

Prediction of tumor-specific splicing from somatic mutations as a source of neoantigen candidatesSemantic proximity Read ↗

Prediction of tumor-specific splicing from somatic mutations as a source of neoantigen candidatesSemantic proximity Read ↗

<tt>neoepiscope</tt> improves neoepitope prediction with multi-variant phasingSemantic proximity Read ↗

RNA Transcription and Splicing Errors as a Source of Cancer Frameshift Neoantigens for VaccinesSemantic proximity Read ↗

Neoantigen Load, Antigen Presentation Machinery, and Immune Signatures Determine Prognosis in Clear Cell Renal Cell Carcinoma.Semantic proximity Read ↗

Variable Mutation Expression in Human Cancers: A "Hide-and-Seek" Mechanism Linked to Differential MHC-I Presentation Dynamics.Semantic proximity Read ↗

A library of Neo Open Reading Frame peptides (NOPs) as a sustainable resource of common neoantigens in up to 50% of cancer patientsSemantic proximity Read ↗

Multi-omics discovery of exome-derived neoantigens in hepatocellular carcinomaSemantic proximity Read ↗

Enhanced mutanome analysis towards the induction of neoepitope-reactive T-cell responses for personalized immunotherapy of pancreatic cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.