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The Proteasomal Deubiquitinating Enzyme PSMD14 Regulates Macroautophagy by Controlling Golgi-to-ER Retrograde Transport.

Cells - 23 Mar 2020

Bustamante Hianara A, Cereceda Karina, González Alexis E, Valenzuela Guillermo E, Cheuquemilla Yorka, Hernández Sergio, Arias-Muñoz Eloisa, Cerda-Troncoso Cristóbal, Bandau Susanne, Soza Andrea, Kausel Gudrun, Kerr Bredford, Mardones Gonzalo A, Cancino Jorge, Hay Ronald T, Rojas-Fernandez Alejandro, Burgos Patricia V

Abstract excerpt

Ubiquitination regulates several biological processes, however the role of specific members of the ubiquitinome on intracellular membrane trafficking is not yet fully understood. Here, we search for ubiquitin-related genes implicated in protein membrane trafficking performing a High-Content siRNA Screening including 1187 genes of the human "ubiquitinome" using amyloid precursor protein (APP) as a reporter. We...

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Identifiers

PMID: 32210007
DOI: 10.3390/cells9030777
PMCID: PMC7140897

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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