Article
The Sensory Coding of Warm Perception.
Neuron - 3 Jun 2020
Paricio-Montesinos Ricardo, Schwaller Frederick, Udhayachandran Annapoorani, Rau Florian, Walcher Jan, Evangelista Roberta, Vriens Joris, Voets Thomas, Poulet James F A, Lewin Gary R
Abstract excerpt
Humans detect skin temperature changes that are perceived as warm or cool. Like humans, mice report forepaw skin warming with perceptual thresholds of less than 1°C and do not confuse warm with cool. We identify two populations of polymodal C-fibers that signal warm. Warm excites one population, whereas it suppresses the ongoing cool-driven firing of the other. In the absence of the thermosensitive TRPM2 or TRPV1...
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