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Article

Epigenome-wide association studies for common human diseases.

Nature reviews. Genetics - 12 Jul 2011

Rakyan Vardhman K, Down Thomas A, Balding David J, Beck Stephan

Abstract excerpt

Despite the success of genome-wide association studies (GWASs) in identifying loci associated with common diseases, a substantial proportion of the causality remains unexplained. Recent advances in genomic technologies have placed us in a position to initiate large-scale studies of human disease-associated epigenetic variation, specifically variation in DNA methylation. Such epigenome-wide association studies...

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PMID: 21747404
DOI: 10.1038/nrg3000
PMCID: PMC3508712

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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