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Article

The Evolutionary Origins of Recurrent Pancreatic Cancer

19 Mar 2020

Abstract excerpt

Abstract Surgery is the only curative option for stage I/II pancreatic cancer; nonetheless, most patients will experience a recurrence after surgery and die of their disease. To identify novel opportunities for management of recurrent pancreatic cancer, we performed whole-exome or targeted sequencing of 10 resected primary cancers and matched intrapancreatic recurrences or distant metastases. We identified that...

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PMID: 32193223
DOI: 10.1158/2159-8290.cd-19-1508

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