Article
Genomic Concordance Between Primary and Oligo-Recurrent Lesions in Pancreatobiliary Cancer.
Journal of hepato-biliary-pancreatic sciences - 1 Apr 2026
Sonoda Keita, Hayashi Hideyuki, Kitago Minoru, Abe Yuta, Hasegawa Yasushi, Hori Shutaro, Tanaka Masayuki, Nakano Yutaka, Nishihara Hiroshi, Kitagawa Yuko
Abstract excerpt
BACKGROUND/PURPOSE: The introduction of oligo-recurrence (OR) as a subtype of metastasis offered new hope, suggesting that local therapies may lead to prolonged survival/cure in selected cases. This study compared the genomic alterations between primary tumors and matched OR lesions in patients with pancreatic ductal adenocarcinoma (PDAC) and cholangiocarcinoma (CCA). METHODS: Eight patients with OR of PDAC or...
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