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Article

[Association between cytochrome p4502c9 polymorphisms and losartan dosing in hypertensive patients].

Revista medica de Chile - 1 Dec 2019

Pedreros-Rosales Cristian, Jalil Milad Roberto, Lagos Lucero Marcela, Solari Gajardo Sandra

Abstract excerpt

Background Losartan is widely used in many clinicals settings. Its dosage is related to the genetic characteristics of CYP2C9 enzymatic activity, which metabolizes losartan to its active form E-3174, responsible for the antihypertensive effect. Aims To identify the frequency of allelic variants CYP2C9*2 and CYP2C9*3 in hypertensive patients and to compare genotypes with a healthy Chilean population. To relate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32186616
DOI: 10.4067/S0034-98872019001201527

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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