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Article

CYP2C9*3 allelic variant is associated with metabolism of irbesartan in Chinese population.

European journal of clinical pharmacology - 1 Oct 2005

Hong Xiumei, Zhang Shanchun, Mao Guangyun, Jiang Shanqun, Zhang Yan, Yu Yunxian, Tang Genfu, Xing Houxun, Xu Xiping

Abstract excerpt

OBJECTIVE: There is considerable variability in the individual pharmaceutical dosages required to achieve optimal therapeutic effects, which may be due to environmental or genetic factors. The objective of this study was to test the presence of the CYP2C9*3 allelic variant in the Chinese population and to investigate the association of this variant with both metabolism and therapeutic efficacy of irbesartan on...

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Identifiers

PMID: 16094537
DOI: 10.1007/s00228-005-0976-8

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