Article
Association of EPAS1 and PPARA Gene Polymorphisms with High-Altitude Headache in Chinese Han Population.
BioMed research international - 1 Jan 2020
Shen Yang, Zhang Jihang, Yang Jie, Liu Chuan, Bian Shizhu, Zhang Chen, Yu Jie, Gao Xubin, Huang Lan
Abstract excerpt
BACKGROUND: High-altitude headache (HAH) is the most common complication after high-altitude exposure. Hypoxia-inducible factor- (HIF-) related genes have been confirmed to contribute to high-altitude acclimatization. We aim to investigate a possible association between HIF-related genes and HAH in the Chinese Han population. METHODS: In total, 580 healthy Chinese Han volunteers were recruited in Chengdu (500 m)...
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