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Article

Analysis of High-altitude Syndrome and the Underlying Gene Polymorphisms Associated with Acute Mountain Sickness after a Rapid Ascent to High-altitude.

Scientific reports - 16 Dec 2016

Yu Jie, Zeng Ying, Chen Guozhu, Bian Shizhu, Qiu Youzhu, Liu Xi, Xu Baida, Song Pan, Zhang Jihang, Qin Jun, Huang Lan

Abstract excerpt

To investigated the objective indicators and potential genotypes for acute mountain sickness (AMS). 176 male subjects were evaluated for symptoms scores and physiological parameters at 3700 m. EPAS1 gene polymorphisms were explored and verified effects of potential genotypes on pulmonary function by inhaled budesonide. The incidence of AMS was 53.98% (95/176). The individuals who suffered from headache with...

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Identifiers

PMID: 27982053
DOI: 10.1038/srep38323
PMCID: PMC5159877

Genes

EPAS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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