Article
Molecular characterization of sorted malignant B cells from patients clinically identified with mantle cell lymphoma.
Experimental hematology - 1 Apr 2020
Hansen Marcus Høy, Cédile Oriane, Blum Mia Koldby, Hansen Simone Valentin, Ebbesen Lene Hyldahl, Bentzen Hans Herluf Nørgaard, Thomassen Mads, Kruse Torben A, Kavan Stephanie, Kjeldsen Eigil, Kristensen Thomas Kielsgaard, Haaber Jacob, Abildgaard Niels, Nyvold Charlotte Guldborg
Abstract excerpt
Mantle cell lymphoma (MCL) is a tumor with a poor prognosis. A few studies have examined the molecular landscape by next-generation sequencing and provided valuable insights into recurrent lesions driving this heterogeneous cancer. However, none has attempted to cross-link the individual genomic and transcriptomic profiles in sorted MCL cells to perform individual molecular characterizations of the lymphomas....
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