Article
Clinical subtypes and molecular characteristics of serrated polyposis syndrome.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association - 1 Jun 2013
Guarinos Carla, Sánchez-Fortún Cristina, Rodríguez-Soler María, Pérez-Carbonell Lucía, Egoavil Cecilia, Juárez Miriam, Serradesanferm Anna, Bujanda Luis, Fernández-Bañares Fernando, Cubiella Joaquín, de-Castro Luisa, Guerra Ana, Aguirre Elena, Herreros-de-Tejada Alberto, Bessa Xavier, Herráiz Maite, Marín-Gabriel José-Carlos, Balmaña Judith, Cuatrecasas Miriam, Balaguer Francesc, Castells Antoni, Soto José-Luis, Alenda Cristina, Payá Artemio, Jover Rodrigo
Abstract excerpt
BACKGROUND & AIMS: We investigated clinical and molecular differences between the different phenotypes of serrated polyposis syndrome (SPS) and the frequency of mutations in BRAF or KRAS in polyps from patients with SPS. METHODS: We collected data on clinical and demographic characteristics of 50 patients who fulfilled the criteria for SPS. Polymerase chain reaction and sequence analysis were used to identify...
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