Article
Phenotype and polyp landscape in serrated polyposis syndrome: a series of 100 patients from genetics clinics.
The American journal of surgical pathology - 1 Jun 2012
Rosty Christophe, Buchanan Daniel D, Walsh Michael D, Pearson Sally-Ann, Pavluk Erika, Walters Rhiannon J, Clendenning Mark, Spring Kevin J, Jenkins Mark A, Win Aung K, Hopper John L, Sweet Kevin, Frankel Wendy L, Aronson Melyssa, Gallinger Steve, Goldblatt Jack, Woodall Sonja, Arnold Julie, Walker Neal I, Jass Jeremy R, Parry Susan, Young Joanne P
Abstract excerpt
Serrated polyposis syndrome (SPS), also known as hyperplastic polyposis, is a syndrome of unknown genetic basis defined by the occurrence of multiple serrated polyps in the large intestine and associated with an increased risk of colorectal cancer (CRC). There are a variety of SPS presentations, which may encompass a continuum of phenotypes modified by environmental and genetic factors. To explore the phenotype...
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