Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-wide expression profile of sporadic gastric cancers with microsatellite instability.

European journal of cancer (Oxford, England : 1990) - 1 Feb 2009

D'Errico Mariarosaria, de Rinaldis Emanuele, Blasi Monica F, Viti Valentina, Falchetti Mario, Calcagnile Angelo, Sera Francesco, Saieva Calogero, Ottini Laura, Palli Domenico, Palombo Fabio, Giuliani Alessandro, Dogliotti Eugenia

Abstract excerpt

Gastric cancers with mismatch repair (MMR) inactivation are characterised by microsatellite instability (MSI). In this study, the transcriptional profile of 38 gastric cancers with and without MSI was analysed. Unsupervised analysis showed that the immune and apoptotic gene networks efficiently discriminated these two cancer types. Hierarchical clustering analysis revealed numerous gene expression changes...

Topics

Join the communities discussing this publication.

DNA Mismatch Repair
Down-Regulation
Gene Expression Profiling
Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Microsatellite Instability

Oligonucleotide Array Sequence Analysis

Stomach Neoplasms

Source

Identifiers

PMID: 19081245
DOI: 10.1016/j.ejca.2008.10.032

Genes

MBD4
MLH1
MRE11
SMUG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-wide expression profile of sporadic gastric cancers with microsatellite instability.PMID 19081245Read ↗

DNA Copy-Number Alterations Underlie Gene Expression Differences between Microsatellite Stable and Unstable Colorectal CancersSemantic proximity Read ↗

Heterogeneity of MSI-H gastric cancer identifies a subtype with worse survivalSemantic proximity Read ↗

Molecular features and prognostic factors of locally advanced microsatellite instability-high gastric cancer.Semantic proximity Read ↗

Potent therapeutic strategy in gastric cancer with microsatellite instability-high and/or deficient mismatch repairSemantic proximity Read ↗

Clinicopathological and molecular alterations in early gastric cancers with the microsatellite instability-high phenotype.Semantic proximity Read ↗

Characterization of the immune escape phenotype of human gastric cancers with and without high-frequency microsatellite instability.Semantic proximity Read ↗

Microsatellite Instability Analysis in Gastric Carcinomas of Moroccan Patients.Semantic proximity Read ↗

Interrelationship between microsatellite instability and microRNA in gastrointestinal cancer.Semantic proximity Read ↗

Colorectal cancers with microsatellite instability display mRNA expression signatures characteristic of increased immunogenicitySemantic proximity Read ↗

Assessing molecular subtypes of gastric cancer: microsatellite unstable and Epstein-Barr virus subtypes. Methods for detection and clinical and pathological implicationsSemantic proximity Read ↗

Causes and consequences of microsatellite instability in gastric carcinogenesis.Semantic proximity Read ↗

mRNA/microRNA gene expression profile in microsatellite unstable colorectal cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.