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Proteomic and transcriptomic profiling of Pten gene‐knockout mouse model of prostate cancer

12 Mar 2020

Abstract excerpt

BACKGROUND: The prostate-specific phosphatase and tensin homolog deleted on chromosome 10 (Pten) gene-conditional knockout (KO) mouse carcinogenesis model is highly desirable for studies of prostate cancer biology and chemoprevention due to its close resemblance of primary molecular defect and many histopathological features of human prostate cancer including androgen response and disease progression from...

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PMID: 32162714
DOI: 10.1002/pros.23972

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