Article
Identification of novel functional CpG-SNPs associated with Type 2 diabetes and birth weight.
Aging - 4 Apr 2021
Liu Rui-Ke, Lin Xu, Wang Zun, Greenbaum Jonathan, Qiu Chuan, Zeng Chun-Ping, Zhu Yong-Yao, Shen Jie, Deng Hong-Wen
Abstract excerpt
Genome-wide association studies (GWASs) have identified hundreds of genetic loci for type 2 diabetes (T2D) and birth weight (BW); however, a large proportion of the total trait heritability remains unexplained. The previous studies were generally focused on individual traits and largely failed to identify the majority of the variants that play key functional roles in the etiology of the disease. Here, we aim to...
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