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Article

Cirrhosis Hampers Early and Rapid Normalization of Natural Killer Cell Phenotype and Function in Hepatitis C Patients Undergoing Interferon-Free Therapy.

Frontiers in immunology - 1 Jan 2020

Perpiñán Elena, Pérez-Del-Pulgar Sofía, Londoño María-Carlota, Mariño Zoe, Bartres Concepción, González Patricia, García-López Mireia, Pose Elisa, Lens Sabela, Maini Mala K, Forns Xavier, Koutsoudakis George

Abstract excerpt

Background: Chronic hepatitis C virus (HCV) infection impairs natural killer (NK) cell phenotype and function. Whether restoration of NK cells occurs after successful interferon (IFN)-free therapies remains a controversial issue. Aim: To analyze how HCV-related liver cirrhosis impacts changes in NK cells prior and post-IFN-free therapies. Methods: NK cell analysis by multicolor flow cytometry was performed in...

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Identifiers

PMID: 32161581
DOI: 10.3389/fimmu.2020.00129
PMCID: PMC7052355

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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