Article
Features and distribution of CD8 T cells with human leukocyte antigen class I-specific receptor expression in chronic hepatitis C.
Hepatology (Baltimore, Md.) - 1 Nov 2007
Bonorino Paula, Leroy Vincent, Dufeu-Duchesne Tania, Tongiani-Dashan Stefania, Sturm Nathalie, Pernollet Martine, Vivier Eric, Zarski Jean-Pierre, Marche Patrice N, Jouvin-Marche Evelyne
Abstract excerpt
UNLABELLED: CD8(+) T cells represent a sizable component of the liver inflammatory infiltrate in chronic hepatitis C and are thought to contribute to immune-mediated tissue injury. Because chronic stimulation may promote the expression by CD8(+) T cells of distinct human leukocyte antigen class I-specific natural killer cell receptors (NKRs) susceptible to both inhibiting effector functions and promoting cell...
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