Article
Natural killer cell phenotype modulation and natural killer/T-cell interplay in nucleos(t)ide analogue-treated hepatitis e antigen-negative patients with chronic hepatitis B.
Hepatology (Baltimore, Md.) - 1 Dec 2015
Boni Carolina, Lampertico Pietro, Talamona Lavinia, Giuberti Tiziana, Invernizzi Federica, Barili Valeria, Fisicaro Paola, Rossi Marzia, Cavallo Maria Cristina, Vecchi Andrea, Pedrazzi Giuseppe, Alfieri Arianna, Colombo Massimo, Missale Gabriele, Ferrari Carlo
Abstract excerpt
UNLABELLED: Natural killer (NK) and hepatitis B virus (HBV)-specific T cells are functionally impaired in chronic hepatitis B (CHB). Understanding to what extent nucleos(t)ide analogue (NUC) therapy can improve T- and NK-cell responses is important in the perspective of immunomonitoring strategies for a safe and earlier NUC withdrawal and of novel combination therapies based on modulation of antiviral immunity....
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