Methylation Statuses of H19DMR and KvDMR at WT2 in Wilms Tumors in Taiwan.

Abstract excerpt

Wilms tumor is the most common pediatric renal malignancy. Several genetic loci have been shown to be associated with its formation. Genetic or epigenetic aberrations at WT1 and WT2 loci have been implicated in the etiology of the majority of sporadic Wilms tumors. In our previous study, most Wilms tumors tested negative for both constitutional mutations and somatic mutations in the WT1 gene. Thus, WT2 may play...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to RNA, Long Noncoding
• Share to Chromosome Aberrations
• Share to CpG Islands