Article

Identification of Molecular Biomarkers in Taiwanese Patients with Wilms Tumor Using a Methylation-Specific Multiplex Ligation-Dependent Probe Amplification (MS-MLPA)-Based Approach

2020-09-28

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Wilms tumor is a solid tumor that frequently occurs in children. Genetic or epigenetic aberrations in <italic>WT1</italic> and <italic>WT2</italic> loci are implicated in its etiology. Moreover, tumor suppressor genes are frequently silenced by methylation in this tumor. <bold>Methods:</bold> In the present study, we analyzed the methylation statuses of promoter...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f7dd926d-130b-5a82-8725-0af0acfbb2d9
DOI: 10.21203/rs.3.rs-80694/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Identification of Molecular Biomarkers in Taiwanese Patients with Wilms Tumor Using a Methylation-Specific Multiplex Ligation-Dependent Probe Amplification (MS-MLPA)-Based ApproachDOI 10.21203/rs.3.rs-80694/v1Read

Genetic variation frequencies in Wilms' tumor: A meta-analysis and systematic review.Semantic proximity Read

Identification of Prognosis-Related RBPs to Reveal The Role of RNA Binding Proteins in the Progression and Prognosis of Wilms’ TumorSemantic proximity Read

Genetic and Epigenetic Drivers of Wilms Tumor Predisposition in Russian Pediatric Patients: A Multicenter Study.Semantic proximity Read

Wilms' tumor gene 1 in hematological malignancies: friend or foe?Semantic proximity Read

Genomic imbalances pinpoint potential oncogenes and tumor suppressors in Wilms tumorsSemantic proximity Read

The genetic factors contributing to the development of Wilm's tumor and their clinical utility in its diagnosis and prognosis.Semantic proximity Read

Exploration of biological significance of m6A-related genes in Wilms tumorSemantic proximity Read

Methylation Statuses of H19DMR and KvDMR at WT2 in Wilms Tumors in Taiwan.Semantic proximity Read

Retrospective analysis of FFPE based Wilms' Tumor samples through copy number and somatic mutation related Molecular Inversion Probe Based Array.Semantic proximity Read

Wilms TumorSemantic proximity Read

Novel epigenetic signature, molecular subtypes and insights into IGF2/H19 dysregulation in Wilms tumour revealed by methylomic and transcriptomic profilingSemantic proximity Read

Integrative Transcriptomic Profiling Reveals Novel Biomarkers in Wilms TumorSemantic proximity Read