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Article

WT1 mutation and 11P15 loss of heterozygosity predict relapse in very low-risk wilms tumors treated with surgery alone: a children's oncology group study.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 20 Feb 2011

Perlman Elizabeth J, Grundy Paul E, Anderson James R, Jennings Lawrence J, Green Daniel M, Dome Jeffrey S, Shamberger Robert C, Ruteshouser E Cristy, Huff Vicki

Abstract excerpt

PURPOSE: Children's Oncology Group defines very low-risk Wilms tumors (VLRWT) as stage I favorable histology Wilms tumors weighing less than 550 g in children younger than 24 months of age. VLRWTs may be treated with nephrectomy alone. However, 10% to 15% of VLRWTs relapse without chemotherapy. P...

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Source

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Identifiers

PMID: 21189373
DOI: 10.1200/JCO.2010.31.5192
PMCID: PMC3056654

Genes

CTNNB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21189373-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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