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Article

N-degron-mediated degradation and regulation of mitochondrial PINK1 kinase.

Current genetics - 1 Aug 2020

Eldeeb Mohamed A, Ragheb Mohamed A

Abstract excerpt

Parkinson's disease (PD) is a progressive neurodegenerative condition characterized by a gradual loss of a specific group of dopaminergic neurons in the substantia nigra. Importantly, current treatments only address the symptoms of PD, yet not the underlying molecular causes. Concomitantly, the function of genes that cause inherited forms of PD point to mitochondrial dysfunction as a major contributor in the...

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PMID: 32157382
DOI: 10.1007/s00294-020-01062-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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