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Article

Function and characteristics of PINK1 in mitochondria.

Oxidative medicine and cellular longevity - 1 Jan 2013

Matsuda Satoru, Kitagishi Yasuko, Kobayashi Mayumi

Abstract excerpt

Mutations in phosphatase and tensin homologue-induced kinase 1 (PINK1) cause recessively inherited Parkinson's disease, a neurodegenerative disorder linked to mitochondrial dysfunction. Studies support the notion of neuroprotective roles for the PINK1, as it protects cells from damage-mediated mitochondrial dysfunction, oxidative stress, and cell apoptosis. PARL is a mitochondrial resident rhomboid serine...

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Source

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Identifiers

PMID: 23533695
DOI: 10.1155/2013/601587
PMCID: PMC3600171

Genes

PINK1
PARL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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