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Article

Identification of key differentially expressed genes and gene mutations in breast ductal carcinoma in situ using RNA-seq analysis.

World journal of surgical oncology - 10 Mar 2020

Zhu Congyuan, Hu Hao, Li Jianping, Wang Jingli, Wang Ke, Sun Jingqiu

Abstract excerpt

BACKGROUND: The aim of this study was to identify the key differentially expressed genes (DEGs) and high-risk gene mutations in breast ductal carcinoma in situ (DCIS). METHODS: Raw data (GSE36863) were downloaded from the database of Gene Expression Omnibus (GEO), including three DCIS samples (DCIS cell lines MCF10.DCIS, Sum102, and Sum225) and one normal control sample (normal mammary epithelial cell line...

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Share to Breast Neoplasms
Share to Carcinoma, Intraductal, Noninfiltrating

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Line, Tumor

Share to Gene Expression Regulation, Neoplastic

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Share to Polymorphism, Single Nucleotide

Share to Sequence Analysis, RNA

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Source

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Identifiers

PMID: 32156290
DOI: 10.1186/s12957-020-01820-z
PMCID: PMC7063758

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