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Article

The decreased expression of IKBKE in systemic lupus erythematosus.

Clinical rheumatology - 1 Sept 2020

Zhu Tingting, Hong Jiaqi, Shuai Zongwen, Xu Shengqian, Qian Danfeng, Hong Xiaojie, Liu Yaoguang, Chen Min, Meng Ziyuan, Zheng Lijun, Zheng Danlin, Zhang Xuejun, Liu Lu

Abstract excerpt

OBJECTIVE: The IKBKE has been proven to be associated with systemic lupus erythematosus (SLE) in a genome-wide association study (GWAS) conducted by our group. The objective of the recent study is to investigate the contribution of IKBKE functional variants (rs2297550) to SLE. METHODS: We detected the regulatory effect of rs2297550 on IKBKE expression by expression quantitative trait loci (eQTL) study. Then, we...

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Identifiers

PMID: 32146614
DOI: 10.1007/s10067-020-05006-6
PMCID: PMC7426285

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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