Article
Overexpression of wysR gene enhances wuyiencin production in ΔwysR3 mutant strain of Streptomyces albulus var. wuyiensis strain CK-15.
Journal of applied microbiology - 1 Sept 2020
Wei Q, Aung A, Liu B, Ma J, Shi L, Zhang K, Ge B
Abstract excerpt
AIM: The aim of the present work was to investigate the overexpression of the wysR gene in Streptomyces albulus var. wuyiensis strain CK-15 based on the ΔwysR3 mutant strain including the effect on morphological development, wuyiencin production and antibacterial activity. At the same time, we report a new rapid method for producing genetically engineered strains for industrial production of wuyiencin. METHODS...
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