Activation of Cryptic Antibiotic Biosynthetic Gene Clusters Guided by RNA-seq Data from Both Streptomyces ansochromogenes and ΔwblA

Abstract excerpt

With the increase of drug resistance caused by the improper use and abuse of antibiotics, human beings are facing a global health crisis. Sequencing of Streptomyces genomes revealed the presence of an important reservoir of secondary metabolic gene clusters for previously unsuspected products with potentially valuable bioactivity. It has therefore become necessary to activate these cryptic pathways through...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genomics and Phylogenetic Studies
• Share to Marine Sponges and Natural Products
• Share to Microbial Natural Products and Biosynthesis