Total skin-sparing mastectomy in BRCA mutation carriers.

doi:10.1245/s10434-013-3230-0

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Article

Total skin-sparing mastectomy in BRCA mutation carriers.

Annals of surgical oncology - 1 Jan 2014

Peled Anne Warren, Irwin Chetan S, Hwang E Shelley, Ewing Cheryl A, Alvarado Michael, Esserman Laura J

Abstract excerpt

BACKGROUND: Total skin-sparing mastectomy (TSSM) with preservation of the nipple-areolar complex skin has become increasingly accepted as an oncologically safe procedure. Oncologic outcomes after TSSM in BRCA mutation carriers have not been well-studied. METHODS: We identified 53 BRCA-positive patients who underwent bilateral TSSM for prophylactic (26 patients) or therapeutic indications (27 patients) from 2001...

Topics

Adult
BRCA1 Protein
BRCA2 Protein
Breast Neoplasms
Female
Follow-Up Studies
Heterozygote
Humans
Mastectomy
Middle Aged
Mutation
Neoplasm Invasiveness

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasm Recurrence, Local

Neoplasm Staging

Organ Sparing Treatments

Patient Selection

Prognosis

Prospective Studies

Source

Open in PubMed

Identifiers

PMID: 23982256
DOI: 10.1245/s10434-013-3230-0

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