Article
SNP rs12982687 affects binding capacity of lncRNA UCA1 with miR-873-5p: involvement in smoking-triggered colorectal cancer progression.
Cell communication and signaling : CCS - 6 Mar 2020
Fu Yang, Zhang Yizheng, Cui Jinyuan, Yang Ge, Peng Sanfei, Mi Wunan, Yin Xiangya, Yu Yang, Jiang Jianwu, Liu Qi, Qin Yiyu, Xu Wen
Abstract excerpt
BACKGROUND: This investigation was arranged to elucidate whether single nucleotide polymorphisms (SNPs) of lncRNA UCA1 was implicated in elevating colorectal cancer (CRC) risk by interacting with environmental exposures. METHODS: LncRNASNP database was firstly adopted to predict SNPs that possibly affected binding of UCA1 with miRNAs and then the interactive effect of SNPs and environmental exposure on CRC risk...
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