Article
A variant rs6214 within IGF-1 confers risk for ulcerative colitis in Chinese Han populations.
Functional & integrative genomics - 15 Dec 2022
Wang Huiping, Wang Jin, Geng Chunsong, Wang Cong, Gu Rongrong, Zhu Zhansheng
Abstract excerpt
Insulin growth factor-1 (IGF-1) has been found to correlate with various diseases such as cancer and cardiovascular diseases including ulcerative colitis (UC). The present study aimed to investigate the plausible association of rs6214 (C > T) within IGF-1 and UC susceptibility in Chinese Han populations. A total of 977 UC patients and 1029 healthy controls were enrolled, and rs6214 was genotyped with PCR and...
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