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Article

Single nucleotide polymorphisms in microRNA binding sites: implications in colorectal cancer.

TheScientificWorldJournal - 1 Jan 2014

Bhaumik Panchalee, Gopalakrishnan Chandrasekhar, Kamaraj Balu, Purohit Rituraj

Abstract excerpt

Cancer is a complex genetic disorder, characterised by uncontrolled cell proliferation and caused by altered expression of oncogenes and tumour suppressor genes. When cell proliferation pertains to colon, it is called colorectal cancer. Most of colorectal cancer causing genes are potential targets for the miRNA (microRNA) that bind to 3'UTR (untranslated regions) of mRNA and inhibit translation. Mutations...

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Identifiers

PMID: 25654126
DOI: 10.1155/2014/547154
PMCID: PMC4310495

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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