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Advances in the role of STAT3 in macrophage polarization

4 Apr 2023

Abstract excerpt

The physiological processes of cell growth, proliferation, differentiation, and apoptosis are closely related to STAT3, and it has been demonstrated that aberrant STAT3 expression has an impact on the onset and progression of a number of inflammatory immunological disorders, fibrotic diseases, and malignancies. In order to produce the necessary biological effects, macrophages (M0) can be polarized into...

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PMID: 37081874
DOI: 10.3389/fimmu.2023.1160719

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