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Article

Pinosylvin Shifts Macrophage Polarization to Support Resolution of Inflammation.

Molecules (Basel, Switzerland) - 8 May 2021

Kivimäki Konsta, Leppänen Tiina, Hämäläinen Mari, Vuolteenaho Katriina, Moilanen Eeva

Abstract excerpt

Pinosylvin is a natural stilbenoid found particularly in Scots pine. Stilbenoids are a group of phenolic compounds identified as protective agents against pathogens for many plants. Stilbenoids also possess health-promoting properties in humans; for instance, they are anti-inflammatory through their suppressing action on proinflammatory M1-type macrophage activation. Macrophages respond to environmental changes...

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Identifiers

PMID: 34066748
DOI: 10.3390/molecules26092772
PMCID: PMC8125806

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